השוואת שיטות

	יחס העברת המגנוטיזציה	NODDI
תחום	הדמיה עצבית	הדמיה עצבית
משפחה	Process / pipeline	Process / pipeline
שנת המקור	1989	2012
הוגה השיטה	Stephen Wolff	Hui Zhang
סוג	Tissue microstructure characterization	Microstructural white matter mapping
מקור מכונן	Wolff, S. D., & Balaban, R. S. (1989). Magnetization transfer contrast (MTC) and tissue water proton relaxation in vivo. Journal of Magnetic Resonance Imaging, 10(2), 135–148.	Zhang, H., Schneider, T., Wheeler-Kingshott, C. A., & Alexander, D. C. (2012). NODDI: practical in vivo neurite orientation dispersion and density imaging of the human brain. NeuroImage, 61(4), 1000–1016.
כינויים	MTR, magnetization transfer, MT imaging	NODDI, neurite density mapping
קשורות	3	3
תקציר	Magnetisation Transfer Ratio (MTR) is an MRI method that measures the exchange of magnetization between free water protons and protons bound to macromolecules (primarily myelin lipids and proteins). Introduced by Wolff and Balaban in 1989, MTR reflects tissue macromolecular content and is particularly sensitive to myelination, providing a non-invasive estimate of myelin density.	Neurite Orientation Dispersion and Density Imaging (NODDI) is a biophysical diffusion MRI model that quantifies microstructural properties of white matter: neurite density (axonal density), orientation dispersion (fiber coherence), and isotropic diffusion (free water or cerebrospinal fluid). Introduced by Zhang and colleagues in 2012, NODDI provides biologically interpretable metrics directly linking diffusion MRI signals to tissue microstructure.