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COSY×הד-ספין ב-NMR×
תחוםספקטרוסקופיהספקטרוסקופיה
משפחהProcess / pipelineProcess / pipeline
שנת המקור19761950
הוגה השיטהWüthrich KurtErwin Hahn
סוגTwo-dimensional pulse sequenceSpectroscopic pulse sequence
מקור מכונןAue, W. P., Bartholdi, E., & Ernst, R. R. (1976). Two-dimensional spectroscopy. Application to nuclear magnetic resonance. The Journal of Chemical Physics, 64(5), 2229-2246. DOI ↗Hahn, E. L. (1950). Spin echoes. Physical Review, 80(4), 580-594. DOI ↗
כינוייםCOSY NMR, 2D COSY, 1H-1H COSYCPMG pulse sequence, spin-echo NMR
קשורות44
תקצירCorrelation Spectroscopy (COSY) is a two-dimensional NMR technique that correlates proton chemical shifts through scalar coupling (J-coupling), revealing which protons are magnetically coupled and hence bonded through multiple bonds. Developed by Aue, Bartholdi, and Ernst in 1976, COSY became one of the most important tools in structural elucidation, enabling chemists to map out proton connectivity patterns and deduce molecular topology without isotopic labeling.The spin-echo is a fundamental nuclear magnetic resonance (NMR) pulse sequence technique introduced by Erwin Hahn in 1950. It uses a 90-degree radiofrequency pulse followed by a 180-degree refocusing pulse to create an echo, effectively reversing the effects of magnetic field inhomogeneities and allowing accurate measurement of spin relaxation properties. This technique is essential in modern NMR spectroscopy for both one-dimensional and multidimensional experiments.
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ScholarGateהשוואת שיטות: COSY · NMR Spin-Echo. אוחזר בתאריך 2026-06-18 מתוך https://scholargate.app/he/compare