השוואת שיטות

	מדד הערכת מחלת אלצהיימר – קוגניטיבי	מבחן קוגניטיבי של אדנברוק (ACE)
תחום	נוירופסיכולוגיה	נוירופסיכולוגיה
משפחה	Process / pipeline	Process / pipeline
שנת המקור	1984	2000
הוגה השיטה	William Rosen	Padasalai Mathuranath
סוג	Clinician-administered cognitive scale for Alzheimer's disease	Clinician-administered comprehensive cognitive examination
מקור מכונן	Rosen, W. G., Mohs, R. C., & Davis, K. L. (1984). A new rating scale for Alzheimer's disease. American Journal of Psychiatry, 141(11), 1356-1364.	Mathuranath, P. S., Nestor, P. J., Berrios, G. E., Rakowicz, W., & Hodges, J. R. (2000). A brief cognitive test battery to differentiate Alzheimer's disease and frontotemporal dementia. Neurology, 55(11), 1613-1620.
כינויים	ADAS-Cog, ADAS-Cog14, ADAS-Cog13	ACE, ACE-R, ACE-III, Addenbrooke Cognitive Examination
קשורות	5	5
תקציר	The Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog) is a clinician-administered cognitive assessment instrument designed specifically to measure cognitive decline in Alzheimer's disease. Developed by Rosen, Mohs, and Davis in 1984 and published in the American Journal of Psychiatry, the ADAS-Cog has become the gold standard outcome measure in pharmaceutical trials of antidementia drugs. It is sensitive to disease progression and capable of detecting cognitive change over periods as brief as 6–12 months.	The Addenbrooke's Cognitive Examination (ACE) is a brief yet comprehensive clinician-administered cognitive battery designed to assess multiple cognitive domains and differentiate between types of dementia. Originally developed by Mathuranath and colleagues at Cambridge University in 2000, the ACE was created to address limitations of single-domain screening tools. The revised version (ACE-R, 2006) and further refined version (ACE-III, 2013) provide updated norms and improved sensitivity. The ACE-R and ACE-III are particularly valuable for distinguishing Alzheimer's disease from frontotemporal dementia.