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| Uudelleenkiteytys× | Kolonnikromatografia× | |
|---|---|---|
| Tieteenala | Kemia | Kemia |
| Menetelmäperhe | Process / pipeline | Process / pipeline |
| Syntyvuosi≠ | early 19th century | 1903 |
| Kehittäjä≠ | Organic chemistry tradition | Mikhail Tsvet |
| Tyyppi≠ | Purification technique | Chromatographic separation technique |
| Alkuperäislähde≠ | Pavia, D. L., Lampman, G. M., Kriz, G. S., & Engel, R. G. (2014). A Small-Scale Approach to Organic Laboratory Techniques (4th ed.). Cengage Learning. ISBN: 978-1285749297 | Skoog, D. A., Holler, F. J., & Crouch, S. R. (2017). Principles of Instrumental Analysis (7th ed.). Cengage Learning. ISBN: 978-1305577213 |
| Rinnakkaisnimet | crystallization purification, recrystallisation | liquid chromatography, column liquid chromatography |
| Liittyvät | 3 | 3 |
| Tiivistelmä≠ | Recrystallization is a classical purification technique in which a solid compound is dissolved in hot solvent, then allowed to crystallize upon cooling, yielding pure crystals while impurities remain in solution. Practiced for centuries in chemistry laboratories, recrystallization remains one of the most effective and accessible methods for purifying organic solids, especially when the target compound has low solubility at low temperatures. | Column chromatography is a liquid separation technique in which a stationary phase (typically silica gel or alumina) is packed into a vertical column, and a mobile phase (solvent) percolates through it to separate mixture components. Pioneered by Mikhail Tsvet in 1903, column chromatography remains the workhorse of organic chemistry laboratories for purifying reaction products and isolating target compounds. |
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