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| Pragmaattinen seulontatestien arviointi× | Kohorttitutkimus× | |
|---|---|---|
| Tieteenala | Epidemiologia | Epidemiologia |
| Menetelmäperhe | Process / pipeline | Process / pipeline |
| Syntyvuosi≠ | 2000s-2010s (formalized with PRECIS framework) | Mid-20th century (formal epidemiological design codified ~1950s) |
| Kehittäjä≠ | Pragmatic trial framework: Schwartz & Lellouch (1967); PRECIS tool: Thorpe et al. (2009) | Doll & Hill (British Doctors Study, 1951); Snow (cholera, 1854) |
| Tyyppi≠ | Observational / quasi-experimental evaluation design | Observational longitudinal study design |
| Alkuperäislähde≠ | Thorpe, K. E., Zwarenstein, M., Oxman, A. D., Treweek, S., Furberg, C. D., Altman, D. G., & Chalkidou, K. (2009). A pragmatic-explanatory continuum indicator summary (PRECIS): a tool to help trial designers. Journal of Clinical Epidemiology, 62(5), 464-475. DOI ↗ | Rothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755641 |
| Rinnakkaisnimet | pragmatic diagnostic screen evaluation, real-world screening evaluation, effectiveness-oriented screening study, PRECIS-guided screening evaluation | longitudinal study, follow-up study, panel study, incidence study |
| Liittyvät≠ | 5 | 6 |
| Tiivistelmä≠ | A pragmatic screening test evaluation assesses the real-world effectiveness of a screening instrument under routine clinical or public-health conditions — rather than the tightly controlled, ideal-participant settings of explanatory studies. It asks whether the screening tool performs adequately in the actual populations and workflows where it will be deployed, prioritising external validity and implementation relevance over maximally controlled internal conditions. | A cohort study assembles a group of individuals who share a common starting point — typically freedom from the outcome of interest — and follows them over time to observe who develops the outcome. By comparing incidence rates between exposed and unexposed subgroups, researchers can estimate relative risk and absolute risk differences. Cohort studies are the gold-standard observational design for measuring disease incidence and establishing temporal relationships between exposure and outcome. |
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