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[KÄÄNNÖS PUUTTUU]×Satunnaistettu kontrolloitu tutkimus (RCT)×
TieteenalaKoesuunnitteluKoesuunnittelu
MenetelmäperheProcess / pipelineHypothesis test
Syntyvuosi19671948
KehittäjäDaniel Schwartz and Joseph LellouchJames Lind (early precursor, 1747); modern formulation: Austin Bradford Hill & Medical Research Council (1948)
TyyppiExperimental design — pragmatic trialInterventional comparative study
AlkuperäislähdeSchwartz, D., & Lellouch, J. (1967). Explanatory and pragmatic attitudes in therapeutical trials. Journal of Chronic Diseases, 20(8), 637–648. DOI ↗Schulz, K.F., Altman, D.G., Moher, D., for the CONSORT Group (2010). CONSORT 2010 Statement: Updated Guidelines for Reporting Parallel Group Randomised Trials. BMJ, 340, c332. DOI ↗
RinnakkaisnimetpRCT, pragmatic trial, practical clinical trial, real-world RCTRCT, randomised controlled trial, clinical trial, Randomize Kontrollü Çalışma (RCT) Tasarımı
Liittyvät47
TiivistelmäA pragmatic randomized controlled trial (pRCT) tests whether an intervention works under ordinary, real-world conditions — broad eligibility, flexible delivery, and routine care settings. Participants are still randomly assigned to treatment or control, preserving causal inference, but the study is designed to reflect the diversity and variability of actual practice rather than the ideal conditions of an explanatory trial. The defining framework is the PRECIS-2 tool, which maps any RCT along nine pragmatic-to-explanatory dimensions.A randomized controlled trial (RCT) is the gold standard experimental design in clinical and health research, in which participants are randomly allocated to a treatment group or a control group so that the effect of an intervention can be measured with the highest possible degree of internal validity. The modern parallel-group RCT was formalized by Austin Bradford Hill and the Medical Research Council in their landmark streptomycin trial of 1948, and its reporting is governed today by the CONSORT 2010 guidelines (Schulz et al., 2010).
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ScholarGateVertaile menetelmiä: Pragmatic Randomized Controlled Trial · Randomized Controlled Trial. Haettu 2026-06-18 osoitteesta https://scholargate.app/fi/compare