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Pragmaattinen monihaarainen koe×Monikäsivälineinen koe×
TieteenalaKoesuunnitteluKoesuunnittelu
MenetelmäperheProcess / pipelineProcess / pipeline
Syntyvuosi1967 (pragmatic trial concept); multi-arm extensions 1990s–2000s1990s–2000s (clinical formalization); multi-arm concept implicit in ANOVA-era factorial designs
KehittäjäSchwartz & Lellouch (pragmatic framing); extended to multi-arm settings in clinical and health services researchDeveloped within clinical trials methodology; formalized by Parmar, Royston and colleagues (UK MRC CTU, early 2000s)
TyyppiExperimental designExperimental design
AlkuperäislähdeThorpe, K. E., Zwarenstein, M., Oxman, A. D., Treweek, S., Furberg, C. D., Altman, D. G., ... & Chalkidou, K. (2009). A pragmatic-explanatory continuum indicator summary (PRECIS): a tool to help trial designers. Journal of Clinical Epidemiology, 62(5), 464-475. DOI ↗Royston, P., Parmar, M. K. B., & Qian, W. (2003). Novel designs for multi-arm clinical trials with survival outcomes with an application in ovarian cancer. Statistics in Medicine, 22(14), 2239–2256. DOI ↗
Rinnakkaisnimetpragmatic multi-arm trial, multi-arm pragmatic RCT, pragmatic multi-treatment experiment, PMATmulti-arm trial, multiple-arm experiment, multi-group experiment, many-arm design
Liittyvät65
TiivistelmäA pragmatic multi-arm experiment is an experimental design that simultaneously compares three or more interventions (arms) under real-world conditions rather than tightly controlled laboratory settings. It combines the broad eligibility, flexible delivery, and effectiveness orientation of pragmatic trials with the statistical efficiency of multi-arm structures, allowing researchers to evaluate multiple treatments or treatment variants against each other or a control within a single study, minimizing the resources and time required relative to running separate pairwise trials.A multi-arm experiment simultaneously compares three or more treatment or intervention conditions — each called an arm — against a shared control or against one another. By testing multiple alternatives in a single study, it yields more information per participant than running separate two-group experiments sequentially, while controlling the overall Type I error rate through pre-specified comparison strategies.
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ScholarGateVertaile menetelmiä: Pragmatic Multi-Arm Experiment · Multi-arm experiment. Haettu 2026-06-18 osoitteesta https://scholargate.app/fi/compare