Vertaile menetelmiä
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| Paritettu tapausselä-kontrollitutkimus× | Tapaus-verrokkitutkimus – havainnoiva epidemiologinen asetelma× | |
|---|---|---|
| Tieteenala | Epidemiologia | Epidemiologia |
| Menetelmäperhe | Process / pipeline | Process / pipeline |
| Syntyvuosi≠ | 1950s–1970s | 1950s (formal methodology); precursors in the 1920s |
| Kehittäjä≠ | Brian MacMahon and others; systematised by Schlesselman (1982) | Janet Lane-Claypon (early precursors, 1926); formalized by Brian MacMahon and Jerome Cornfield in the 1950s–1960s |
| Tyyppi≠ | Observational analytic design | Observational analytic study design |
| Alkuperäislähde≠ | Rothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755474 | Schlesselman, J.J. (1982). Case-Control Studies: Design, Conduct, Analysis. Oxford University Press. ISBN: 978-0195027860 |
| Rinnakkaisnimet | matched case-referent study, individually matched case-control, pair-matched case-control, matched case-control design | case-referent study, case-control design, retrospective case-control, case-control analysis |
| Liittyvät≠ | 5 | 6 |
| Tiivistelmä≠ | A matched case-control study is an observational epidemiological design in which each case (a person with the disease or outcome of interest) is paired with one or more controls (persons without the outcome) who share one or more characteristics — such as age, sex, or clinical setting — to control confounding. Exposure history is then compared between cases and their matched controls to estimate the odds ratio of the exposure-disease association. | A case-control study is a retrospective observational design in which individuals who have developed a disease or outcome of interest (cases) are compared with individuals who have not (controls) to determine whether prior exposure to a putative risk factor differs between the two groups. The primary measure of association is the odds ratio, which approximates the relative risk when the outcome is rare. Case-control studies are especially efficient for investigating rare diseases and generating etiological hypotheses. |
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