Vertaile menetelmiä

	Endemic Compartmental Models (SIS, SIRS, SIRV)	Lisääntymisluku (R0 ja Rt)	SEIR-malli
Tieteenala	Epidemiologia	Epidemiologia	Epidemiologia
Menetelmäperhe	Regression model	Regression model	Regression model
Syntyvuosi	2000	1990	1991
Kehittäjä	Herbert Hethcote	Diekmann, Heesterbeek & Metz	Kermack & McKendrick; Anderson & May
Tyyppi	Compartmental ODE model	Threshold parameter for epidemic spread	Deterministic compartmental ODE model
Alkuperäislähde	Hethcote, H. W. (2000). The mathematics of infectious diseases. SIAM Review, 42(4), 599–653.	Diekmann, O., Heesterbeek, J. A. P., & Metz, J. A. J. (1990). On the definition and the computation of the basic reproduction ratio R0. Journal of Mathematical Biology, 28(4), 365–382.	Anderson, R. M., & May, R. M. (1991). Infectious Diseases of Humans: Dynamics and Control. Oxford University Press. ISBN: 978-0-19-854040-3
Rinnakkaisnimet	SIS Model, SIRS Model, SIRV Model, Endemic Disease Models	Basic Reproduction Ratio, Effective Reproduction Number, Net Reproduction Number, Temel Üreme Sayısı	Susceptible-Exposed-Infectious-Recovered Model, SEIR Compartmental Model, Latent Period Epidemic Model, SEIR Bulaşıcı Hastalık Modeli
Liittyvät	3	2	3
Tiivistelmä	Endemic compartmental models extend the classical SIR framework to capture diseases that persist indefinitely in a population rather than burning out after a single epidemic wave. The SIS model allows recovered individuals to return to susceptibility immediately; SIRS introduces temporary immunity before loss; SIRV adds a vaccinated compartment. Together these models are foundational tools for studying diseases such as influenza, gonorrhea, and seasonal pathogens where reinfection or waning immunity is epidemiologically central.	The basic reproduction number R0 is the expected number of secondary infections produced by a single infectious individual introduced into a fully susceptible population. Formally defined and computationally grounded by Diekmann, Heesterbeek, and Metz in 1990 using the next-generation matrix approach, R0 serves as the central threshold parameter in mathematical epidemiology: if R0 > 1, an epidemic can establish itself; if R0 < 1, the outbreak dies out. The effective reproduction number Rt extends this to partially immune or partially susceptible populations over time.	The SEIR model is a deterministic compartmental model that partitions a closed population into four epidemiological states: Susceptible (S), Exposed (E), Infectious (I), and Recovered (R). It extends the classic SIR framework by explicitly incorporating a latent period during which individuals have been infected but are not yet infectious. The model was systematically formalized by Anderson and May (1991) and remains a cornerstone of mathematical epidemiology for diseases with non-negligible incubation periods.