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برنامه‌ریزی مسیر سنتز×کروماتوگرافی لایه نازک×
حوزهشیمیشیمی
خانوادهProcess / pipelineProcess / pipeline
سال پیدایش19691956
پدیدآورElias James CoreyEgon Stahl
نوعStrategic planning methodologyChromatographic separation technique
منبع بنیادینCorey, E. J., & Cheng, X. M. (1991). The Logic of Chemical Synthesis. John Wiley & Sons. ISBN: 978-0471096092Sherma, J. (2003). Planar Chromatography. Analytical Chemistry, 75(12), 2783–2811. DOI ↗
نام‌های دیگرretrosynthesis, retrosynthetic analysis, synthetic route designTLC, planar chromatography
مرتبط33
خلاصهSynthesis route planning, grounded in retrosynthetic analysis, is a strategic approach to designing efficient chemical syntheses. Formalized by Elias James Corey in the 1960s (earning him the Nobel Prize in 1990), this methodology systematically deconstructs target molecules into simpler precursors and starting materials, enabling chemists to discover logical, economical, and practical synthesis routes.Thin-Layer Chromatography (TLC) is a planar chromatographic technique that separates compounds based on their differential affinities for a mobile and stationary phase. Developed by Egon Stahl in 1956, TLC remains one of the most accessible and widely used analytical methods in organic and inorganic chemistry, laboratories, and quality control.
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ScholarGateمقایسهٔ روش‌ها: Synthesis Route Planning · Thin-Layer Chromatography. بازیابی‌شده در 2026-06-18 از https://scholargate.app/fa/compare