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مطالعه مورد-شاهدی تودرتوی گذشته‌نگر×مطالعه مورد-شاهدی×
حوزهاپیدمیولوژیاپیدمیولوژی
خانوادهProcess / pipelineProcess / pipeline
سال پیدایش1973 (formal description); widely adopted in epidemiology from 1980s onward1950s (formal methodology); precursors in the 1920s
پدیدآورNested case-control formalized by Mantel (1973); retrospective application via historical cohort recordsJanet Lane-Claypon (early precursors, 1926); formalized by Brian MacMahon and Jerome Cornfield in the 1950s–1960s
نوعObservational analytic study designObservational analytic study design
منبع بنیادینMantel, N. (1973). Synthetic retrospective studies and related topics. Biometrics, 29(3), 479–486. link ↗Schlesselman, J.J. (1982). Case-Control Studies: Design, Conduct, Analysis. Oxford University Press. ISBN: 978-0195027860
نام‌های دیگرretrospective NCC, nested case-control within retrospective cohort, case-control nested in historical cohort, nested CCRcase-referent study, case-control design, retrospective case-control, case-control analysis
مرتبط56
خلاصهA retrospective nested case-control study is an efficient observational design in which cases and matched controls are sampled from within an already-assembled retrospective cohort. Exposure data are retrieved from historical records only for selected participants, dramatically reducing data-collection costs while retaining most of the analytic power of the full cohort. It is widely used in pharmacoepidemiology, occupational health, and disease-registry research.A case-control study is a retrospective observational design in which individuals who have developed a disease or outcome of interest (cases) are compared with individuals who have not (controls) to determine whether prior exposure to a putative risk factor differs between the two groups. The primary measure of association is the odds ratio, which approximates the relative risk when the outcome is rare. Case-control studies are especially efficient for investigating rare diseases and generating etiological hypotheses.
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ScholarGateمقایسهٔ روش‌ها: Retrospective nested case-control · Case-control study. بازیابی‌شده در 2026-06-15 از https://scholargate.app/fa/compare