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حوزهشیمیشیمیشیمی
خانوادهProcess / pipelineProcess / pipelineProcess / pipeline
سال پیدایشearly 19th century19031956
پدیدآورOrganic chemistry traditionMikhail TsvetEgon Stahl
نوعPurification techniqueChromatographic separation techniqueChromatographic separation technique
منبع بنیادینPavia, D. L., Lampman, G. M., Kriz, G. S., & Engel, R. G. (2014). A Small-Scale Approach to Organic Laboratory Techniques (4th ed.). Cengage Learning. ISBN: 978-1285749297Skoog, D. A., Holler, F. J., & Crouch, S. R. (2017). Principles of Instrumental Analysis (7th ed.). Cengage Learning. ISBN: 978-1305577213Sherma, J. (2003). Planar Chromatography. Analytical Chemistry, 75(12), 2783–2811. DOI ↗
نام‌های دیگرcrystallization purification, recrystallisationliquid chromatography, column liquid chromatographyTLC, planar chromatography
مرتبط333
خلاصهRecrystallization is a classical purification technique in which a solid compound is dissolved in hot solvent, then allowed to crystallize upon cooling, yielding pure crystals while impurities remain in solution. Practiced for centuries in chemistry laboratories, recrystallization remains one of the most effective and accessible methods for purifying organic solids, especially when the target compound has low solubility at low temperatures.Column chromatography is a liquid separation technique in which a stationary phase (typically silica gel or alumina) is packed into a vertical column, and a mobile phase (solvent) percolates through it to separate mixture components. Pioneered by Mikhail Tsvet in 1903, column chromatography remains the workhorse of organic chemistry laboratories for purifying reaction products and isolating target compounds.Thin-Layer Chromatography (TLC) is a planar chromatographic technique that separates compounds based on their differential affinities for a mobile and stationary phase. Developed by Egon Stahl in 1956, TLC remains one of the most accessible and widely used analytical methods in organic and inorganic chemistry, laboratories, and quality control.
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ScholarGateمقایسهٔ روش‌ها: Recrystallization · Column Chromatography · Thin-Layer Chromatography. بازیابی‌شده در 2026-06-18 از https://scholargate.app/fa/compare