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خانوادهProcess / pipelineProcess / pipeline
سال پیدایش1967 (pragmatic trial concept); multi-arm extensions 1990s–2000s1990s–2000s (systematic formalization)
پدیدآورSchwartz & Lellouch (pragmatic framing); extended to multi-arm settings in clinical and health services researchBuilding on cluster randomization (Donner & Klar) and multi-arm trial methods developed in clinical and public health research
نوعExperimental designExperimental design
منبع بنیادینThorpe, K. E., Zwarenstein, M., Oxman, A. D., Treweek, S., Furberg, C. D., Altman, D. G., ... & Chalkidou, K. (2009). A pragmatic-explanatory continuum indicator summary (PRECIS): a tool to help trial designers. Journal of Clinical Epidemiology, 62(5), 464-475. DOI ↗Donner, A., & Klar, N. (2000). Design and Analysis of Cluster Randomization Trials in Health Research. Arnold. ISBN: 978-0340691533
نام‌های دیگرpragmatic multi-arm trial, multi-arm pragmatic RCT, pragmatic multi-treatment experiment, PMATmulti-arm cluster RCT, cluster-randomized multi-group trial, multi-arm group-randomized trial, CRCT multi-arm
مرتبط66
خلاصهA pragmatic multi-arm experiment is an experimental design that simultaneously compares three or more interventions (arms) under real-world conditions rather than tightly controlled laboratory settings. It combines the broad eligibility, flexible delivery, and effectiveness orientation of pragmatic trials with the statistical efficiency of multi-arm structures, allowing researchers to evaluate multiple treatments or treatment variants against each other or a control within a single study, minimizing the resources and time required relative to running separate pairwise trials.A cluster randomized multi-arm experiment assigns intact groups — such as schools, clinics, or villages — rather than individuals to three or more experimental conditions simultaneously. Randomization occurs at the cluster level to prevent contamination between arms, while the multi-arm structure allows simultaneous evaluation of several interventions against a common control or each other, improving efficiency over a series of two-arm studies.
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ScholarGateمقایسهٔ روش‌ها: Pragmatic Multi-Arm Experiment · Cluster Randomized Multi-Arm Experiment. بازیابی‌شده در 2026-06-17 از https://scholargate.app/fa/compare