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حوزهطراحی آزمایشطراحی آزمایش
خانوادهProcess / pipelineProcess / pipeline
سال پیدایش1990s–2000s2000s–2010s (MAMS framework formalized c. 2003–2011)
پدیدآورEvolved from clinical trial methodology; consolidated in the 1990s–2000sPatrick Royston, Mahesh Parmar, and colleagues (multi-arm multi-stage framework); further developed by James Wason, Thomas Jaki and others
نوعExperimental design (pilot/feasibility)Experimental design
منبع بنیادینThabane, L., Ma, J., Chu, R., Cheng, J., Ismaila, A., Rios, L. P., Robson, R., Thabane, M., Giangregorio, L., & Goldsmith, C. H. (2010). A tutorial on pilot studies: The what, why and how. BMC Medical Research Methodology, 10(1), 1. DOI ↗Royston, P., Parmar, M. K. B., & Qian, W. (2003). Novel designs for multi-arm clinical trials with survival outcomes with an application in ovarian cancer. Statistics in Medicine, 22(14), 2239–2256. DOI ↗
نام‌های دیگرpilot multi-arm trial, feasibility multi-arm study, pilot parallel-arm experiment, preliminary multi-arm experimentMAMS design, multi-arm adaptive trial, adaptive platform trial, response-adaptive multi-arm experiment
مرتبط63
خلاصهA pilot multi-arm experiment is a small-scale preliminary trial that tests the feasibility, logistics, and parameter estimates needed to plan a full-scale multi-arm study. It simultaneously evaluates two or more active treatment arms alongside a control, providing early evidence on recruitment rates, retention, protocol adherence, variability, and likely effect sizes before committing to a resource-intensive definitive experiment.An adaptive multi-arm experiment simultaneously evaluates several treatment conditions against a common control and modifies the trial in real time based on accumulating data — dropping ineffective arms early, reallocating participants toward promising ones, or adjusting sample sizes — all while controlling error rates. The approach maximizes information gained per participant and reduces the time and cost required to identify effective treatments relative to running sequential separate trials.
ScholarGateمجموعه‌داده
  1. v1
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  3. PUBLISHED
  1. v1
  2. 2 منابع
  3. PUBLISHED

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ScholarGateمقایسهٔ روش‌ها: Pilot Multi-Arm Experiment · Adaptive Multi-Arm Experiment. بازیابی‌شده در 2026-06-17 از https://scholargate.app/fa/compare