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NMR Spin-Echo×همبستگی کوانتومی منفرد ناهمگن (HSQC)×
حوزهطیف‌سنجیطیف‌سنجی
خانوادهProcess / pipelineProcess / pipeline
سال پیدایش19501980
پدیدآورErwin HahnAnil Kumar
نوعSpectroscopic pulse sequenceHeteronuclear correlation sequence
منبع بنیادینHahn, E. L. (1950). Spin echoes. Physical Review, 80(4), 580-594. DOI ↗Bodenhausen, G., & Ruben, D. J. (1981). Natural abundance nitrogen-15 NMR by enhanced heteronuclear spectroscopy. Chemical Physics Letters, 69(2), 185-189. DOI ↗
نام‌های دیگرCPMG pulse sequence, spin-echo NMRHSQC NMR, 1H-13C HSQC, heteronuclear correlation
مرتبط44
خلاصهThe spin-echo is a fundamental nuclear magnetic resonance (NMR) pulse sequence technique introduced by Erwin Hahn in 1950. It uses a 90-degree radiofrequency pulse followed by a 180-degree refocusing pulse to create an echo, effectively reversing the effects of magnetic field inhomogeneities and allowing accurate measurement of spin relaxation properties. This technique is essential in modern NMR spectroscopy for both one-dimensional and multidimensional experiments.Heteronuclear Single-Quantum Coherence (HSQC) is a 2D NMR technique that correlates proton and carbon-13 (or other heteronuclei) chemical shifts through one-bond coupling constants (1JHX). Developed in the early 1980s, HSQC rapidly became the workhorse of structural chemistry because it directly maps which carbons bear which protons, providing a comprehensive view of carbon skeleton connectivity and substitution patterns.
ScholarGateمجموعه‌داده
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  3. PUBLISHED

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ScholarGateمقایسهٔ روش‌ها: NMR Spin-Echo · HSQC. بازیابی‌شده در 2026-06-17 از https://scholargate.app/fa/compare