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خانوادهSurvival analysisSurvival analysis
سال پیدایش19491958
پدیدآورBoag, J. W.Kaplan, E. L. & Meier, P.
نوعParametric mixture survival modelNon-parametric survival estimator
منبع بنیادینBoag, J. W. (1949). Maximum Likelihood Estimates of the Proportion of Patients Cured. Journal of the Royal Statistical Society B, 11(1), 15–53. link ↗Kaplan, E. L. & Meier, P. (1958). Nonparametric Estimation from Incomplete Observations. Journal of the American Statistical Association, 53(282), 457–481. DOI ↗
نام‌های دیگرcure fraction model, cure rate model, bounded cumulative hazard model, İyileşme Modeli (Mixture Cure Model)product-limit estimator, km curve, kaplan-meier sağkalım analizi
مرتبط22
خلاصهThe mixture cure model, first proposed by Boag in 1949 for cancer survival data, is a parametric survival model that explicitly accounts for a fraction of subjects who will never experience the event of interest — the so-called cured or immune fraction. It is the appropriate tool whenever the Kaplan-Meier curve levels off into a long, stable plateau rather than continuing to decline, indicating that a proportion of subjects are permanently event-free.The Kaplan-Meier estimator, introduced by Kaplan and Meier in 1958, is a non-parametric method that estimates the survival curve — the probability of remaining event-free over time — from right-censored time-to-event data. The log-rank test is the companion procedure used to compare survival curves between groups.
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ScholarGateمقایسهٔ روش‌ها: Mixture Cure Model · Kaplan-Meier. بازیابی‌شده در 2026-06-15 از https://scholargate.app/fa/compare