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آزمایش غشای کوریوآلانتوئیک (CAM)×غزل‌ریسی الکترواستاتیکی×
حوزهزیست‌موادزیست‌مواد
خانوادهProcess / pipelineProcess / pipeline
سال پیدایش19741934
پدیدآورJudah FolkmanAnton Formhals
نوعDevelopmental biology assayFiber fabrication process
منبع بنیادینFolkman, J. (1974). Tumor angiogenesis: therapeutic implications. New England Journal of Medicine, 285(21), 1182-1186. link ↗Formhals, A. (1934). Process and apparatus for preparing artificial threads. U.S. Patent 1,975,504. link ↗
نام‌های دیگرchick embryo chorioallantoic membrane, angiogenesis assay, CAM angiogenesis modelelectrospun fiber production, electrostatic fiber spinning
مرتبط43
خلاصهThe chorioallantoic membrane (CAM) assay is a well-established in vivo model for studying angiogenesis (new blood vessel formation) and evaluating the pro- or anti-angiogenic properties of biomaterials, drugs, and bioactive molecules. Developed by Judah Folkman in the 1970s, the assay uses the highly vascularized CAM of developing chick embryos as a platform for implanting test materials and observing vascular response. The CAM provides a transparent, immunologically naive microenvironment with rapid and reproducible neovascularization, making it ideal for screening angiogenic potential and assessing biomaterial biocompatibility.Electrospinning is an electrostatic fiber fabrication process that uses a high electric field to draw polymer solutions or melts into nanoscale fibers. Developed by Anton Formhals in the 1930s and refined by researchers including Darrell Reneker in the 1990s, the technique has become foundational to biomaterials engineering, enabling the creation of porous scaffolds for tissue engineering and drug delivery systems.
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ScholarGateمقایسهٔ روش‌ها: CAM Assay · Electrospinning. بازیابی‌شده در 2026-06-20 از https://scholargate.app/fa/compare