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Diseño de estudio de casos y controles×Diseño de estudio de cohortes×
CampoInvestigación clínicaInvestigación clínica
FamiliaProcess / pipelineProcess / pipeline
Año de origen1950s-1970s1970s-1980s
Autor originalJerome L. Schlesselman, Brian MacMahon, Thomas PughDonald Acheson, Olli Miettinen, and others in modern epidemiology
TipoResearch DesignResearch Design
Fuente seminalSchlesselman, J. J. (1982). Case-Control Studies: Design, Conduct, Analysis. Oxford University Press. ISBN: 978-0195027815Miettinen, O. S. (1976). Estimability and estimation in case-referent studies. American Journal of Epidemiology, 103(2), 226–235. DOI ↗
Aliascase-control study, retrospective study, matched case-control, nested case-controlprospective study, follow-up study, longitudinal study, cohort study
Relacionados22
ResumenA case-control study identifies individuals with a disease or outcome (cases) and a comparison group without the outcome (controls), then measures prior exposure retrospectively. Developed in the 1950s–1970s by epidemiologists like Schlesselman and MacMahon, case-control studies are especially efficient for rare diseases, as they sample cases enriched for the outcome, avoiding the need for enormous cohorts. They are a mainstay of clinical epidemiology, observational research, and outbreak investigations.A cohort study follows a group of individuals forward in time from exposure to outcome. Exposed and unexposed participants (or participants with differing exposure levels) are enrolled at baseline, characterized, and observed prospectively until the outcome occurs or the study ends. Cohort studies are fundamental to epidemiology and are the design of choice for establishing causal associations when randomized trials are infeasible or unethical.
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ScholarGateComparar métodos: Case-Control Study Design · Cohort Study Design. Recuperado el 2026-06-17 de https://scholargate.app/es/compare