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Planung von Syntheserouten×Dünnschichtchromatographie×
FachgebietChemieChemie
FamilieProcess / pipelineProcess / pipeline
Entstehungsjahr19691956
UrheberElias James CoreyEgon Stahl
TypStrategic planning methodologyChromatographic separation technique
Wegweisende QuelleCorey, E. J., & Cheng, X. M. (1991). The Logic of Chemical Synthesis. John Wiley & Sons. ISBN: 978-0471096092Sherma, J. (2003). Planar Chromatography. Analytical Chemistry, 75(12), 2783–2811. DOI ↗
Aliasnamenretrosynthesis, retrosynthetic analysis, synthetic route designTLC, planar chromatography
Verwandt33
ZusammenfassungSynthesis route planning, grounded in retrosynthetic analysis, is a strategic approach to designing efficient chemical syntheses. Formalized by Elias James Corey in the 1960s (earning him the Nobel Prize in 1990), this methodology systematically deconstructs target molecules into simpler precursors and starting materials, enabling chemists to discover logical, economical, and practical synthesis routes.Thin-Layer Chromatography (TLC) is a planar chromatographic technique that separates compounds based on their differential affinities for a mobile and stationary phase. Developed by Egon Stahl in 1956, TLC remains one of the most accessible and widely used analytical methods in organic and inorganic chemistry, laboratories, and quality control.
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ScholarGateMethoden vergleichen: Synthesis Route Planning · Thin-Layer Chromatography. Abgerufen am 2026-06-18 von https://scholargate.app/de/compare