Methoden vergleichen

	Sequential Organ Failure Assessment Score	APACHE II Score	Modified Early Warning Score
Fachgebiet	Klinische Diagnostik	Klinische Diagnostik	Klinische Diagnostik
Familie	Process / pipeline	Process / pipeline	Process / pipeline
Entstehungsjahr	1996	1985	2001
Urheber	Jean-Louis Vincent and Rui Moreno	William A. Knaus, et al.	Christian P. Subbe, et al.
Typ	Organ dysfunction and sepsis assessment	ICU severity and mortality prediction	Hospital ward deterioration warning system
Wegweisende Quelle	Vincent, J. L., Moreno, R., Takala, J., et al. (1996). The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfuncti on/failure. Intensive Care Medicine, 22(7), 707-710.	Knaus, W. A., Draper, E. A., Wagner, D. P., & Zimmerman, J. E. (1985). APACHE II: a severity of disease classification system. Critical Care Medicine, 13(10), 818-829.	Subbe, C. P., Kruger, M., Rutherford, P., & Gemmel, L. (2001). Validation of a modified Early Warning Score in medical admissions. QJM: An International Journal of Medicine, 94(10), 521-526.
Aliasnamen	SOFA, Sepsis-related Organ Failure Assessment	APACHE-II, APACHE2	MEWS, Early warning score
Verwandt	3	3	3
Zusammenfassung	The Sequential Organ Failure Assessment (SOFA) score, introduced by Vincent and Moreno in 1996, is a 24-point daily assessment tool that quantifies organ dysfunction across six physiological systems in critically ill patients. It was adopted into the 2016 Sepsis-3 definitions and is now the international standard for identifying and grading sepsis-related organ failure.	The Acute Physiology and Chronic Health Evaluation (APACHE) II score, introduced by Knaus et al. in 1985, is a 71-point severity of illness classification system for critically ill patients. It combines acute physiological parameters, age, and chronic health status to predict intensive care unit (ICU) mortality, facilitating patient risk stratification and research standardization.	The Modified Early Warning Score (MEWS), introduced by Subbe et al. in 2001, is a 14-point alert system designed for rapid detection of clinical deterioration in hospitalized patients. It combines six vital sign and laboratory parameters to identify patients at high risk of rapid decline, enabling early intervention before critical events occur.