Methoden vergleichen
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| Prospektive Evaluation von Screening-Tests× | Prospektive Studie zur diagnostischen Genauigkeit× | |
|---|---|---|
| Fachgebiet | Epidemiologie | Epidemiologie |
| Familie | Process / pipeline | Process / pipeline |
| Entstehungsjahr≠ | 1980s–2000s (STARD 2003, updated 2015) | Formalized 2000s; practice dates to mid-20th century |
| Urheber≠ | Formalized through diagnostic accuracy methodology (Sackett, Haynes, Tugwell; STARD initiative) | Established through STARD initiative (Bossuyt, Reitsma et al., 2000s) |
| Typ≠ | Prospective observational study design | Observational / evaluative study design |
| Wegweisende Quelle≠ | Bossuyt, P. M., Reitsma, J. B., Bruns, D. E., et al. (2015). STARD 2015: An Updated List of Essential Items for Reporting Diagnostic Accuracy Studies. BMJ, 351, h5527. DOI ↗ | Bossuyt, P. M., Reitsma, J. B., Bruns, D. E., Gatsonis, C. A., Glasziou, P. P., Irwig, L., ... & Cohen, J. F. (2015). STARD 2015: an updated list of essential items for reporting diagnostic accuracy studies. BMJ, 351, h5527. DOI ↗ |
| Aliasnamen | prospective diagnostic accuracy study, prospective test performance study, forward-looking screening validation, prospective DTA study | prospective DTA study, prospective test accuracy study, forward-looking diagnostic study, prospective index test evaluation |
| Verwandt | 6 | 6 |
| Zusammenfassung≠ | A prospective screening test evaluation enrolls participants before the outcome is known, applies the screening test and the reference standard in temporal sequence, and measures how accurately the test identifies individuals with or without the target condition. This forward-looking design minimizes workup bias and spectrum bias, producing estimates of sensitivity, specificity, and predictive values that are more generalizable to real clinical or public-health screening contexts than retrospective alternatives. | A prospective diagnostic accuracy study enrolls participants before any test results are known and follows them forward in time to evaluate how well an index test (the test under evaluation) distinguishes individuals with and without a target condition, using a reference standard applied independently. Key accuracy metrics include sensitivity, specificity, positive and negative predictive values, and the area under the ROC curve. The prospective design reduces many biases inherent in retrospective test evaluations. |
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