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Multizentrische Kohortenstudie×Prospektive Kohortenstudie×
FachgebietEpidemiologieEpidemiologie
FamilieProcess / pipelineProcess / pipeline
EntstehungsjahrMid-to-late 20th century (widespread adoption 1970s–1990s)1950s (systematic application); conceptual roots earlier
UrheberDeveloped incrementally through large collaborative epidemiological projects (e.g., Framingham Heart Study consortium expansions, 1948 onward; EPIC study, 1992)Richard Doll and Austin Bradford Hill (landmark application, 1951-1954); cohort methodology formalised by modern epidemiology textbooks
TypObservational longitudinal studyObservational longitudinal study design
Wegweisende QuelleRothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755641Rothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755641
Aliasnamenmultisite cohort study, multi-centre cohort, collaborative cohort study, pooled cohort studylongitudinal cohort study, prospective follow-up study, incidence study, prospective observational cohort
Verwandt66
ZusammenfassungA multicenter cohort study follows defined groups of participants at two or more geographically or institutionally distinct sites over time to estimate incidence, identify risk factors, and quantify associations between exposures and outcomes. By pooling data from multiple centers, it achieves statistical power and population diversity that single-site designs cannot match, making it the workhorse of large-scale epidemiological and clinical research.A prospective cohort study assembles a group of participants who are free of the outcome of interest at baseline, measures their exposures, and then follows them forward in time to record who develops the outcome. By collecting exposure data before outcomes occur, it establishes a clear temporal sequence that supports causal inference — a major advantage over retrospective designs. It is the cornerstone observational method in epidemiology and clinical research.
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ScholarGateMethoden vergleichen: Multicenter cohort study · Prospective Cohort Study. Abgerufen am 2026-06-18 von https://scholargate.app/de/compare