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| Abgleichstudie (Querschnittsepidemiologie)× | Fall-Kontroll-Studie× | |
|---|---|---|
| Fachgebiet | Epidemiologie | Epidemiologie |
| Familie | Process / pipeline | Process / pipeline |
| Entstehungsjahr≠ | Mid-to-late 20th century (formalized ~1970s–1990s) | 1950s (formal methodology); precursors in the 1920s |
| Urheber≠ | Developed within the tradition of observational epidemiology; matching principles codified by Greenland, Rothman, and Kelsey in modern epidemiology texts | Janet Lane-Claypon (early precursors, 1926); formalized by Brian MacMahon and Jerome Cornfield in the 1950s–1960s |
| Typ≠ | Observational epidemiological study design | Observational analytic study design |
| Wegweisende Quelle≠ | Rothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755641 | Schlesselman, J.J. (1982). Case-Control Studies: Design, Conduct, Analysis. Oxford University Press. ISBN: 978-0195027860 |
| Aliasnamen | matched cross-sectional survey, matched prevalence study, matched cross-sectional design, frequency-matched cross-sectional study | case-referent study, case-control design, retrospective case-control, case-control analysis |
| Verwandt≠ | 5 | 6 |
| Zusammenfassung≠ | A matched cross-sectional epidemiological study is an observational design that measures exposure and outcome simultaneously in a population sample while applying matching to control for one or more confounding variables. By pairing or grouping participants on key characteristics such as age, sex, or socioeconomic status before or during analysis, the design reduces confounding bias without requiring longitudinal follow-up, making it efficient for estimating prevalence and cross-sectional associations. | A case-control study is a retrospective observational design in which individuals who have developed a disease or outcome of interest (cases) are compared with individuals who have not (controls) to determine whether prior exposure to a putative risk factor differs between the two groups. The primary measure of association is the odds ratio, which approximates the relative risk when the outcome is rare. Case-control studies are especially efficient for investigating rare diseases and generating etiological hypotheses. |
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