Methoden vergleichen

	Magnetoelastographie	Quantitative Susceptibility Mapping
Fachgebiet	Medizinische Bildgebung	Medizinische Bildgebung
Familie	Process / pipeline	Process / pipeline
Entstehungsjahr	1995	2015
Urheber	Richard Muthupillai	Yong Wang
Typ	MRI-based measurement of tissue stiffness	Quantitative MRI contrast mechanism
Wegweisende Quelle	Muthupillai, R., Lomas, D. J., Rossman, P. J., et al. (1995). Magnetic resonance elastography by direct visualization of propagating acoustic strain waves. Science, 269(5232), 1854-1857.	Wang, Y., Liu, T. (2015). Quantitative susceptibility mapping (QSM): Decoding MRI data for a tissue magnetic biomarker. Magnetic Resonance in Medicine, 73(1), 82-101.
Aliasnamen	MRE, elastography, tissue stiffness mapping	QSM, susceptibility-weighted imaging
Verwandt	5	5
Zusammenfassung	Magnetic Resonance Elastography (MRE) is a non-invasive imaging technique that measures tissue stiffness by encoding the motion of acoustic shear waves into MRI signal and calculating the elastic modulus from wave propagation patterns. Developed by Muthupillai and colleagues in 1995, MRE enables quantitative assessment of tissue mechanics, particularly useful for diagnosing liver fibrosis, cardiac dysfunction, and neurological diseases. It has emerged as a non-invasive alternative to biopsy for staging hepatic fibrosis and is expanding into other organ systems.	Quantitative Susceptibility Mapping (QSM) is a post-processing technique that converts MRI phase data into quantitative susceptibility values, enabling direct visualization and measurement of tissue magnetic properties. Developed by Wang, Liu, and colleagues, QSM transforms phase shifts caused by differences in magnetic susceptibility between tissues into tissue-specific biomarkers. It has revolutionized the sensitivity of MRI to iron, calcium, and other paramagnetic and diamagnetic substances, making it valuable in neurodegenerative disease diagnosis and tissue characterization.