Methoden vergleichen

	Magnetoelastographie	Funktionelles Ultraschall
Fachgebiet	Medizinische Bildgebung	Medizinische Bildgebung
Familie	Process / pipeline	Process / pipeline
Entstehungsjahr	1995	2011
Urheber	Richard Muthupillai	Mickael Tanter
Typ	MRI-based measurement of tissue stiffness	High-framerate doppler imaging for hemodynamics
Wegweisende Quelle	Muthupillai, R., Lomas, D. J., Rossman, P. J., et al. (1995). Magnetic resonance elastography by direct visualization of propagating acoustic strain waves. Science, 269(5232), 1854-1857.	Macé, E., Montaldo, G., Trenholm, S., et al. (2011). Functional ultrasound imaging of the brain. Nature Methods, 8(8), 662-664.
Aliasnamen	MRE, elastography, tissue stiffness mapping	fUS, doppler ultrasound, ultrafast ultrasound
Verwandt	5	5
Zusammenfassung	Magnetic Resonance Elastography (MRE) is a non-invasive imaging technique that measures tissue stiffness by encoding the motion of acoustic shear waves into MRI signal and calculating the elastic modulus from wave propagation patterns. Developed by Muthupillai and colleagues in 1995, MRE enables quantitative assessment of tissue mechanics, particularly useful for diagnosing liver fibrosis, cardiac dysfunction, and neurological diseases. It has emerged as a non-invasive alternative to biopsy for staging hepatic fibrosis and is expanding into other organ systems.	Functional Ultrasound (fUS) is a high-framerate Doppler ultrasound technique that dynamically maps blood flow and hemodynamic changes in vivo with millisecond temporal resolution. Pioneered by Tanter, Macé, and colleagues in the 2010s, fUS enables real-time imaging of microvascular perfusion in the brain and other organs. By combining ultrafast acquisition (1000-5000 frames per second) with Doppler processing, fUS reveals functional activity (hemodynamic changes during stimulation or behavior) and vascular networks with unprecedented spatiotemporal detail.