Methoden vergleichen

	Ärztliche Gesamtbeurteilung der Lupusaktivität (PGA)	Bath Ankylosing Spondylitis Disease Activity Index (BASDAI)
Fachgebiet	Rheumatologie	Rheumatologie
Familie	Process / pipeline	Process / pipeline
Entstehungsjahr	1992	1994
Urheber	Bombardier et al.	Garrett et al.
Typ	Clinician-rated	Patient-reported outcome (PRO)
Wegweisende Quelle	Petri M. Thermodynamic instability in the pathogenesis of lupus nephritis. Nat Rev Rheum. 2016;12(11):635-642.	Garrett S, Jenkinson T, Kennedy LG, Whitelock H, Gaisford P, Calin A. A new approach to defining disease status in ankylosing spondylitis: the Bath Ankylosing Spondylitis Disease Activity Index. The Journal of Rheumatology. 1994;21(12):2286-2291.
Aliasnamen	Physician Global Assessment, PGA-Lupus, Clinician Global Assessment-SLE	BASDAI, BAS-DAI
Verwandt	3	4
Zusammenfassung	The Physician Global Assessment (PGA) is a clinician-rated, single-item measure of overall systemic lupus erythematosus (SLE) disease activity on a visual analogue scale (0–10). Used alongside structured indices like SLEDAI, PGA captures the clinician's integrated judgment of SLE severity, synthesising clinical examination, serology, imaging, and organ-specific findings into a holistic activity score. PGA is simple, practical, and widely used in SLE research and clinical practice as a complementary measure that reflects experienced clinician assessment of disease state.	The BASDAI is a patient-reported outcome measure of disease activity in ankylosing spondylitis (AS), a chronic inflammatory arthropathy affecting the spine and axial skeleton. Introduced by Garrett et al. in 1994, BASDAI uses six simple patient self-report items focused on the cardinal symptoms of AS: fatigue, spinal pain, peripheral joint involvement, and morning stiffness. As a PRO measure, BASDAI is practical for routine monitoring, responsive to treatment, and strongly associated with clinical outcomes and spinal damage progression, making it a cornerstone outcome in AS management and clinical trials.