Methoden vergleichen

	Funktionelles Ultraschall	Quantitative Susceptibility Mapping
Fachgebiet	Medizinische Bildgebung	Medizinische Bildgebung
Familie	Process / pipeline	Process / pipeline
Entstehungsjahr	2011	2015
Urheber	Mickael Tanter	Yong Wang
Typ	High-framerate doppler imaging for hemodynamics	Quantitative MRI contrast mechanism
Wegweisende Quelle	Macé, E., Montaldo, G., Trenholm, S., et al. (2011). Functional ultrasound imaging of the brain. Nature Methods, 8(8), 662-664.	Wang, Y., Liu, T. (2015). Quantitative susceptibility mapping (QSM): Decoding MRI data for a tissue magnetic biomarker. Magnetic Resonance in Medicine, 73(1), 82-101.
Aliasnamen	fUS, doppler ultrasound, ultrafast ultrasound	QSM, susceptibility-weighted imaging
Verwandt	5	5
Zusammenfassung	Functional Ultrasound (fUS) is a high-framerate Doppler ultrasound technique that dynamically maps blood flow and hemodynamic changes in vivo with millisecond temporal resolution. Pioneered by Tanter, Macé, and colleagues in the 2010s, fUS enables real-time imaging of microvascular perfusion in the brain and other organs. By combining ultrafast acquisition (1000-5000 frames per second) with Doppler processing, fUS reveals functional activity (hemodynamic changes during stimulation or behavior) and vascular networks with unprecedented spatiotemporal detail.	Quantitative Susceptibility Mapping (QSM) is a post-processing technique that converts MRI phase data into quantitative susceptibility values, enabling direct visualization and measurement of tissue magnetic properties. Developed by Wang, Liu, and colleagues, QSM transforms phase shifts caused by differences in magnetic susceptibility between tissues into tissue-specific biomarkers. It has revolutionized the sensitivity of MRI to iron, calcium, and other paramagnetic and diamagnetic substances, making it valuable in neurodegenerative disease diagnosis and tissue characterization.