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| CFD-Hämodynamik× | FEA-Knochenumbau× | |
|---|---|---|
| Fachgebiet | Biomechanik | Biomechanik |
| Familie | Process / pipeline | Process / pipeline |
| Entstehungsjahr≠ | 2002 | 1987 |
| Urheber≠ | David Steinman | Rik Huiskes |
| Typ≠ | Multi-physics finite element simulation | Multi-physics finite element pipeline |
| Wegweisende Quelle≠ | Steinman, D. A., Vinh, B., Ethier, C. R., Ojha, M., Cobbold, R. S., & Johnston, K. W. (2002). A numerical simulation of flow in a two-dimensional end-to-side anastomosis model. Journal of Biomechanical Engineering, 115(1), 112-118. link ↗ | Huiskes, R., Weinans, H., Grootenboer, H. J., Dalstra, M., Fudala, B., & Slooff, T. J. (1987). Adaptive bone-remodeling theory applied to prosthetic-design analysis. Journal of Biomechanics, 20(11-12), 1135-1150. DOI ↗ |
| Aliasnamen | Cardiovascular CFD, Blood flow simulation, Hemodynamic simulation | Bone remodeling simulation, Trabecular architecture adaptation, Mechano-regulation |
| Verwandt | 3 | 3 |
| Zusammenfassung≠ | Computational fluid dynamics (CFD) for hemodynamics solves the Navier-Stokes equations to simulate blood flow in realistic vascular geometries. Pioneered by researchers such as David Steinman, CFD hemodynamics reveals complex flow patterns, wall shear stress distributions, and hemodynamic factors implicated in atherosclerosis, aneurysm rupture, and device-induced thrombosis. | Finite element analysis (FEA) for bone remodeling predicts how bone tissue density and architecture adapt to changes in mechanical loading over time. Pioneered by Rik Huiskes and Donald Carter in the 1980s, this computational approach integrates stress analysis with biophysical remodeling rules to simulate the long-term response of bone to disease, aging, or surgical intervention. |
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