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Swelling and Degradation×Elektrospinning×
FagområdeBiomaterialerBiomaterialer
FamilieProcess / pipelineProcess / pipeline
Oprindelsesår19601934
OphavspersonWichterle and LimAnton Formhals
TypeKinetic assayFiber fabrication process
Oprindelig kildeWichterle, O., & Lim, D. (1960). Hydrophilic gels for biological use. Nature, 185(4706), 117-118. DOI ↗Formhals, A. (1934). Process and apparatus for preparing artificial threads. U.S. Patent 1,975,504. link ↗
Aliasserhydrogel swelling, polymer degradation, mass loss assayelectrospun fiber production, electrostatic fiber spinning
Relaterede43
ResuméThe swelling and degradation assay measures how biomaterial scaffolds absorb water (swelling) and lose mass over time due to degradation. Developed by Wichterle and Lim in 1960 for hydrogels, the assay is fundamental for characterizing hydrogels, synthetic polymers, and composite scaffolds intended for tissue engineering. The assay provides quantitative data on swelling kinetics (equilibrium water content, swelling ratio), degradation kinetics (mass loss rate, half-life), and mechanisms of degradation (chain scission, enzymatic breakdown).Electrospinning is an electrostatic fiber fabrication process that uses a high electric field to draw polymer solutions or melts into nanoscale fibers. Developed by Anton Formhals in the 1930s and refined by researchers including Darrell Reneker in the 1990s, the technique has become foundational to biomaterials engineering, enabling the creation of porous scaffolds for tissue engineering and drug delivery systems.
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ScholarGateSammenlign metoder: Swelling and Degradation · Electrospinning. Hentet 2026-06-18 fra https://scholargate.app/da/compare