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Prospektiv undersøgelse af diagnostisk nøjagtighed×Randomiseret klinisk forsøg (RCT)×
FagområdeEpidemiologiEpidemiologi
FamilieProcess / pipelineProcess / pipeline
OprindelsesårFormalized 2000s; practice dates to mid-20th century1948 (first rigorously conducted RCT — MRC streptomycin trial)
OphavspersonEstablished through STARD initiative (Bossuyt, Reitsma et al., 2000s)Austin Bradford Hill; MRC Streptomycin Trial team
TypeObservational / evaluative study designInterventional experimental study
Oprindelig kildeBossuyt, P. M., Reitsma, J. B., Bruns, D. E., Gatsonis, C. A., Glasziou, P. P., Irwig, L., ... & Cohen, J. F. (2015). STARD 2015: an updated list of essential items for reporting diagnostic accuracy studies. BMJ, 351, h5527. DOI ↗Friedman, L. M., Furberg, C. D., DeMets, D. L., Reboussin, D. M., & Granger, C. B. (2015). Fundamentals of Clinical Trials (5th ed.). Springer. ISBN: 978-3319185385
Aliasserprospective DTA study, prospective test accuracy study, forward-looking diagnostic study, prospective index test evaluationRCT, randomized controlled trial, randomised controlled trial, clinical randomized trial
Relaterede66
ResuméA prospective diagnostic accuracy study enrolls participants before any test results are known and follows them forward in time to evaluate how well an index test (the test under evaluation) distinguishes individuals with and without a target condition, using a reference standard applied independently. Key accuracy metrics include sensitivity, specificity, positive and negative predictive values, and the area under the ROC curve. The prospective design reduces many biases inherent in retrospective test evaluations.A randomized clinical trial (RCT) is an experimental study design in which participants are randomly assigned to an intervention group or a control group, then followed prospectively to compare outcomes. Random allocation is the defining feature: it distributes known and unknown confounders across groups by chance, making the RCT the strongest individual study design for establishing causal efficacy of a treatment or intervention under controlled conditions.
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ScholarGateSammenlign metoder: Prospective Diagnostic Accuracy Study · Randomized clinical trial. Hentet 2026-06-18 fra https://scholargate.app/da/compare