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Adaptivt randomiseret kontrolleret forsøg×Adaptivt eksperiment×
FagområdeForsøgsdesignForsøgsdesign
FamilieProcess / pipelineProcess / pipeline
Oprindelsesår1980s–2000s (formalized; earlier sequential testing roots from Wald, 1947)1940s–1970s (sequential foundations); formalised in clinical and behavioural research by 1980s–2000s
OphavspersonDonald Berry and others; foundational adaptive trial methods developed through 1980s–2000s biostatistics literatureAbraham Wald (sequential analysis foundation); expanded by Robbins, Armitage, and others
TypeExperimental design — adaptive variant of RCTExperimental research design
Oprindelig kildeChow, S.-C., & Chang, M. (2008). Adaptive Design Methods in Clinical Trials. Chapman & Hall/CRC. ISBN: 978-1584887690Chow, S. C., & Chang, M. (2008). Adaptive Design Methods in Clinical Trials. Chapman and Hall/CRC. ISBN: 978-1584886761
AliasserAdaptive RCT, Response-adaptive RCT, Adaptive clinical trial, Platform trialadaptive design, response-adaptive randomization, adaptive trial, adaptive randomization
Relaterede65
ResuméAn adaptive randomized controlled trial (adaptive RCT) is an experimental design in which pre-specified rules allow modifications to the trial while it is ongoing — such as changing allocation ratios, dropping underperforming arms, or stopping early for efficacy or futility — based on accumulating interim data. These adaptations are planned before the trial starts and governed by statistical rules to preserve Type I error control and validity.An adaptive experiment is an experimental design in which pre-specified rules allow the protocol to be modified — such as reallocating participants to better-performing arms, stopping early for efficacy or futility, or changing sample size — based on accumulating interim data, while maintaining statistical validity. Adaptive designs are widely used in clinical trials, behavioural economics, and online platform testing to improve efficiency and ethics without sacrificing inferential rigour.
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ScholarGateSammenlign metoder: Adaptive Randomized Controlled Trial · Adaptive Experiment. Hentet 2026-06-17 fra https://scholargate.app/da/compare