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Adaptivt laboratorieeksperiment×Sekventiel Analyse (Gruppesekventielt Design)×
FagområdeForsøgsdesignStatistik
FamilieProcess / pipelineHypothesis test
Oprindelsesår1947 (sequential analysis foundations); adaptive laboratory applications widespread from 1990s1977
OphavspersonRooted in sequential analysis (Abraham Wald, 1947); adaptive clinical/lab designs formalized by Berry and colleagues (1990s–2000s)P. C. O'Brien & T. R. Fleming; P. C. Pocock
TypeAdaptive experimental designSequential / adaptive hypothesis test
Oprindelig kildeBerry, D. A. (2006). Bayesian clinical trials. Nature Reviews Drug Discovery, 5(1), 27–36. DOI ↗O'Brien, P.C. & Fleming, T.R. (1979). A Multiple Testing Procedure for Clinical Trials. Biometrics, 35(3), 549–556. DOI ↗
Aliasseradaptive lab experiment, sequential adaptive laboratory study, response-adaptive laboratory design, adaptive experimental laboratory designsequential testing, group sequential design, interim analysis, Sıralı Analiz (Sequential Testing / Group Sequential Design)
Relaterede55
ResuméAn adaptive laboratory experiment is a controlled experimental design conducted in a laboratory setting where pre-specified decision rules allow modifications to the study — such as sample size, treatment allocation, or stopping criteria — based on accumulating data. Unlike fixed designs, adaptive designs incorporate planned interim analyses that permit the experiment to respond to emerging evidence while maintaining statistical validity and Type I error control.Sequential analysis is a framework for conducting hypothesis tests with pre-planned interim looks at accumulating data, allowing a study to stop early for efficacy or futility while controlling the overall Type I error rate. The group sequential approach was formalised by Pocock (1977) and O'Brien and Fleming (1979), and remains the standard for confirmatory clinical trials and rigorous A/B experiments.
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ScholarGateSammenlign metoder: Adaptive Laboratory Experiment · Sequential Analysis. Hentet 2026-06-15 fra https://scholargate.app/da/compare