Porovnat metody
Prohlédněte si vybrané metody vedle sebe; řádky, které se liší, jsou zvýrazněny.
| UHDRS: Jednotná škála hodnocení Huntingtonovy choroby× | EDSS: Kurtzkeho rozšířená škála stavu postižení× | |
|---|---|---|
| Obor | Neurologie | Neurologie |
| Rodina | Process / pipeline | Process / pipeline |
| Rok vzniku≠ | 1996 | 1983 |
| Tvůrce≠ | Huntington Study Group | John F. Kurtzke |
| Typ≠ | Clinician-rated and performance-based | Clinician-rated |
| Původní zdroj≠ | Huntington Study Group (1996). Unified Huntington's Disease Rating Scale: Reliability and consistency. Movement Disorders, 11(2), 136-142. link ↗ | Kurtzke, J. F. (1983). Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS). Neurology, 33(11), 1444-1452. DOI ↗ |
| Další názvy≠ | UHDRS, Huntington's Rating Scale | Expanded Disability Status Scale |
| Příbuzné | 4 | 4 |
| Shrnutí≠ | The Unified Huntington's Disease Rating Scale (UHDRS) is the comprehensive, multidomain assessment instrument for Huntington's disease, a neurodegenerative disorder caused by expanded CAG trinucleotide repeats. Developed by the Huntington Study Group in 1996, the UHDRS measures motor, cognitive, functional, and psychiatric manifestations of disease. The UHDRS is the gold-standard outcome measure in Huntington's disease clinical trials and longitudinal natural history studies. | The EDSS is the most widely used clinical disability rating scale in multiple sclerosis research and practice. Developed by John Kurtzke in 1983, it provides a 0-10 ordinal scale capturing disease severity across eight neurological functional systems and functional status. The EDSS remains the primary endpoint in MS clinical trials and longitudinal cohort studies, with decades of prognostic and comparative data worldwide. |
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