Porovnat metody
Prohlédněte si vybrané metody vedle sebe; řádky, které se liší, jsou zvýrazněny.
| Jednoslepý vícevětevný experiment× | Randomizovaný kontrolovaný proces s jednosměrným zaslepením× | |
|---|---|---|
| Obor | Plánování experimentů | Plánování experimentů |
| Rodina | Process / pipeline | Process / pipeline |
| Rok vzniku≠ | Mid-to-late 20th century | 1948 (formalized); single-blind variant established in mid-20th century clinical trial methodology |
| Tvůrce≠ | Developed within the clinical trials tradition; formalized by Friedman, Furberg, and DeMets and others in the 20th century | Bradford Hill and colleagues (MRC streptomycin trial, 1948); blinding conventions codified in CONSORT guidelines |
| Typ≠ | Controlled experimental design | Experimental design — blinded randomized trial |
| Původní zdroj≠ | Friedman, L. M., Furberg, C. D., & DeMets, D. L. (2010). Fundamentals of Clinical Trials (4th ed.). Springer. ISBN: 978-1441915849 | Schulz, K. F., Altman, D. G., Moher, D., & CONSORT Group. (2010). CONSORT 2010 statement: Updated guidelines for reporting parallel group randomised trials. BMJ, 340, c332. DOI ↗ |
| Další názvy | single-masked multi-arm trial, single-blind multi-group experiment, unidirectional blinding multi-arm design, SB-MAT | single-masked RCT, single-blind RCT, single-blind trial, SB-RCT |
| Příbuzné | 5 | 5 |
| Shrnutí≠ | A single-blind multi-arm experiment is a controlled experimental design that simultaneously compares three or more treatment conditions while blinding participants — but not investigators — to their group assignment. This configuration reduces response bias driven by participants' expectations, preserves operational feasibility when full blinding is impractical, and allows direct pairwise and omnibus comparisons across multiple arms within a single study. | A single-blind randomized controlled trial (SB-RCT) is a rigorous experimental design in which participants are randomly assigned to treatment or control conditions while remaining unaware of which condition they have received. Investigators, outcome assessors, and data analysts are not blinded. By masking participants, the design eliminates placebo and nocebo response biases on the participant side, while preserving investigator flexibility to administer and monitor the intervention. |
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