Porovnat metody
Prohlédněte si vybrané metody vedle sebe; řádky, které se liší, jsou zvýrazněny.
| Prospektivní kohortová studie× | Případová studie× | |
|---|---|---|
| Obor | Epidemiologie | Epidemiologie |
| Rodina | Process / pipeline | Process / pipeline |
| Rok vzniku≠ | 1950s (systematic application); conceptual roots earlier | 1950s (formal methodology); precursors in the 1920s |
| Tvůrce≠ | Richard Doll and Austin Bradford Hill (landmark application, 1951-1954); cohort methodology formalised by modern epidemiology textbooks | Janet Lane-Claypon (early precursors, 1926); formalized by Brian MacMahon and Jerome Cornfield in the 1950s–1960s |
| Typ≠ | Observational longitudinal study design | Observational analytic study design |
| Původní zdroj≠ | Rothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755641 | Schlesselman, J.J. (1982). Case-Control Studies: Design, Conduct, Analysis. Oxford University Press. ISBN: 978-0195027860 |
| Další názvy | longitudinal cohort study, prospective follow-up study, incidence study, prospective observational cohort | case-referent study, case-control design, retrospective case-control, case-control analysis |
| Příbuzné | 6 | 6 |
| Shrnutí≠ | A prospective cohort study assembles a group of participants who are free of the outcome of interest at baseline, measures their exposures, and then follows them forward in time to record who develops the outcome. By collecting exposure data before outcomes occur, it establishes a clear temporal sequence that supports causal inference — a major advantage over retrospective designs. It is the cornerstone observational method in epidemiology and clinical research. | A case-control study is a retrospective observational design in which individuals who have developed a disease or outcome of interest (cases) are compared with individuals who have not (controls) to determine whether prior exposure to a putative risk factor differs between the two groups. The primary measure of association is the odds ratio, which approximates the relative risk when the outcome is rare. Case-control studies are especially efficient for investigating rare diseases and generating etiological hypotheses. |
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