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Studie adaptivní diagnostické přesnosti×Hodnocení screeningových testů×
OborEpidemiologieEpidemiologie
RodinaProcess / pipelineProcess / pipeline
Rok vzniku2000s–2010s (adaptive designs codified for diagnostics ~2010s)1968 (Wilson-Jungner principles); statistical framework developed 1970s–2000s
TvůrceAdaptation of STARD framework (Bossuyt et al.) combined with adaptive design principles (Jennison & Turnbull; FDA guidance)Wilson & Jungner (WHO criteria, 1968); foundational work by Pepe, Altman, and others in statistical test evaluation
TypAdaptive observational/experimental study designObservational diagnostic / epidemiological evaluation design
Původní zdrojBossuyt, P. M., Reitsma, J. B., Bruns, D. E., Gatsonis, C. A., Glasziou, P. P., Irwig, L., ... & Cohen, J. F. (2015). STARD 2015: an updated list of essential items for reporting diagnostic accuracy studies. BMJ, 351, h5527. DOI ↗Wilson, J. M. G., & Jungner, G. (1968). Principles and Practice of Screening for Disease. World Health Organization. Public Health Papers No. 34. link ↗
Další názvyadaptive DTA study, adaptive diagnostic test evaluation, adaptive test accuracy trial, adaptive STARD studyscreening study, screening performance evaluation, screening accuracy assessment, STE
Příbuzné66
ShrnutíAn adaptive diagnostic accuracy study evaluates how well an index test distinguishes between patients with and without a target condition, while incorporating pre-specified interim analyses that allow modifications — such as sample size re-estimation, threshold adjustment, or subgroup enrichment — based on accumulating data. This design improves efficiency and ethical conduct compared to fixed-sample diagnostic studies, particularly when prior prevalence or test performance data are uncertain.Screening test evaluation is a systematic epidemiological approach for assessing whether a test or program can accurately and cost-effectively identify individuals with a condition before symptoms appear. It quantifies diagnostic performance metrics — sensitivity, specificity, predictive values, and the ROC curve — and evaluates whether a screening program meets established public health criteria for adoption and harm-benefit balance.
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ScholarGatePorovnat metody: Adaptive Diagnostic Accuracy Study · Screening Test Evaluation. Získáno 2026-06-17 z https://scholargate.app/cs/compare