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একক-অন্ধ এলোমেলো নিয়ন্ত্রিত পরীক্ষা×ক্রসওভার র্যান্ডমাইজড কন্ট্রোলড ট্রায়াল×
ক্ষেত্রপরীক্ষামূলক নকশাপরীক্ষামূলক নকশা
পরিবারProcess / pipelineProcess / pipeline
উদ্ভবের বছর1948 (formalized); single-blind variant established in mid-20th century clinical trial methodology1960s (Grizzle 1965 for statistical foundations); widely used in clinical research since the 1970s
প্রবর্তকBradford Hill and colleagues (MRC streptomycin trial, 1948); blinding conventions codified in CONSORT guidelinesEarly formalized by statisticians including Bradford Hill and colleagues in clinical trials; theoretical framework developed by Grizzle (1965) and later Senn (2002)
ধরনExperimental design — blinded randomized trialExperimental within-subject design
মৌলিক উৎসSchulz, K. F., Altman, D. G., Moher, D., & CONSORT Group. (2010). CONSORT 2010 statement: Updated guidelines for reporting parallel group randomised trials. BMJ, 340, c332. DOI ↗Senn, S. (2002). Cross-over Trials in Clinical Research (2nd ed.). Wiley. ISBN: 978-0471496533
অপর নামsingle-masked RCT, single-blind RCT, single-blind trial, SB-RCTcrossover RCT, crossover trial, within-subject RCT, AB/BA crossover design
সম্পর্কিত55
সারসংক্ষেপA single-blind randomized controlled trial (SB-RCT) is a rigorous experimental design in which participants are randomly assigned to treatment or control conditions while remaining unaware of which condition they have received. Investigators, outcome assessors, and data analysts are not blinded. By masking participants, the design eliminates placebo and nocebo response biases on the participant side, while preserving investigator flexibility to administer and monitor the intervention.A crossover randomized controlled trial (crossover RCT) is an experimental design in which each participant receives all study interventions in a randomized sequence, separated by a washout period. Because every participant serves as their own control, within-subject variability is eliminated from the treatment comparison, yielding greater statistical power per participant than a parallel-group RCT of equal size.
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অনুসন্ধানে যান স্লাইড ডাউনলোড করুন

ScholarGateপদ্ধতির তুলনা করুন: Single-blind Randomized Controlled Trial · Crossover Randomized Controlled Trial. 2026-06-17 তারিখে সংগৃহীত, উৎস: https://scholargate.app/bn/compare