পদ্ধতির তুলনা করুন

	পর্যায় III ক্লিনিক্যাল ট্রায়াল	র‍্যান্ডমাইজড ক্লিনিক্যাল ট্রায়াল (RCT)
ক্ষেত্র	মহামারীবিদ্যা	মহামারীবিদ্যা
পরিবার	Process / pipeline	Process / pipeline
উদ্ভবের বছর	1962 (Kefauver-Harris Amendment formalised phased drug development)	1948 (first rigorously conducted RCT — MRC streptomycin trial)
প্রবর্তক	FDA regulatory framework / ICH guidelines	Austin Bradford Hill; MRC Streptomycin Trial team
ধরন	Confirmatory randomised controlled trial	Interventional experimental study
মৌলিক উৎস	Friedman, L. M., Furberg, C. D., DeMets, D. L., Reboussin, D. M., & Granger, C. B. (2015). Fundamentals of Clinical Trials (5th ed.). Springer. ISBN: 978-3319185385	Friedman, L. M., Furberg, C. D., DeMets, D. L., Reboussin, D. M., & Granger, C. B. (2015). Fundamentals of Clinical Trials (5th ed.). Springer. ISBN: 978-3319185385
অপর নাম	Phase 3 trial, confirmatory trial, pivotal trial, Phase III RCT	RCT, randomized controlled trial, randomised controlled trial, clinical randomized trial
সম্পর্কিত	6	6
সারসংক্ষেপ	A Phase III clinical trial is a large-scale, confirmatory randomised controlled trial designed to establish the efficacy and safety of an intervention in the target patient population before regulatory submission. It builds on the signal identified in Phase II, tests the intervention at its proposed dose under controlled conditions, and provides the primary evidence base for marketing authorisation or guideline adoption.	A randomized clinical trial (RCT) is an experimental study design in which participants are randomly assigned to an intervention group or a control group, then followed prospectively to compare outcomes. Random allocation is the defining feature: it distributes known and unknown confounders across groups by chance, making the RCT the strongest individual study design for establishing causal efficacy of a treatment or intervention under controlled conditions.