পদ্ধতির তুলনা করুন
নির্বাচিত পদ্ধতিগুলো পাশাপাশি পর্যালোচনা করুন; যে সারিগুলোয় পার্থক্য আছে সেগুলো চিহ্নিত করা হয়।
| ডাবল-ব্লাইন্ড অ্যাডাপ্টিভ এক্সপেরিমেন্ট× | বহু-বাহু পরীক্ষা× | |
|---|---|---|
| ক্ষেত্র | পরীক্ষামূলক নকশা | পরীক্ষামূলক নকশা |
| পরিবার | Process / pipeline | Process / pipeline |
| উদ্ভবের বছর≠ | Conceptual roots 1970s–1990s; regulatory codification 2004–2019 | 1990s–2000s (clinical formalization); multi-arm concept implicit in ANOVA-era factorial designs |
| প্রবর্তক≠ | Formalized through FDA adaptive design guidance and work by Scott Berry, Donald Berry, and colleagues | Developed within clinical trials methodology; formalized by Parmar, Royston and colleagues (UK MRC CTU, early 2000s) |
| ধরন≠ | Experimental design combining blinding and adaptive modification | Experimental design |
| মৌলিক উৎস≠ | U.S. Food and Drug Administration. (2019). Adaptive Designs for Clinical Trials of Drugs and Biologics: Guidance for Industry. FDA. link ↗ | Royston, P., Parmar, M. K. B., & Qian, W. (2003). Novel designs for multi-arm clinical trials with survival outcomes with an application in ovarian cancer. Statistics in Medicine, 22(14), 2239–2256. DOI ↗ |
| অপর নাম | double-blind adaptive design, blinded adaptive trial, double-blind adaptive RCT, adaptive double-blind study | multi-arm trial, multiple-arm experiment, multi-group experiment, many-arm design |
| সম্পর্কিত≠ | 4 | 5 |
| সারসংক্ষেপ≠ | A double-blind adaptive experiment combines two powerful design features: double-blinding, which conceals treatment assignment from both participants and outcome assessors to prevent bias, and adaptive modification, which allows pre-specified changes to the trial's course — such as sample size re-estimation, allocation ratio shifts, or arm dropping — based on accumulating interim data. The result is a rigorous, bias-protected design that can respond to emerging evidence without compromising inferential validity. | A multi-arm experiment simultaneously compares three or more treatment or intervention conditions — each called an arm — against a shared control or against one another. By testing multiple alternatives in a single study, it yields more information per participant than running separate two-group experiments sequentially, while controlling the overall Type I error rate through pre-specified comparison strategies. |
| ScholarGateডেটাসেট ↗ |
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