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অভিযোজিত এলোমেলো নিয়ন্ত্রিত পরীক্ষা×বহু-বাহু পরীক্ষা×
ক্ষেত্রপরীক্ষামূলক নকশাপরীক্ষামূলক নকশা
পরিবারProcess / pipelineProcess / pipeline
উদ্ভবের বছর1980s–2000s (formalized; earlier sequential testing roots from Wald, 1947)1990s–2000s (clinical formalization); multi-arm concept implicit in ANOVA-era factorial designs
প্রবর্তকDonald Berry and others; foundational adaptive trial methods developed through 1980s–2000s biostatistics literatureDeveloped within clinical trials methodology; formalized by Parmar, Royston and colleagues (UK MRC CTU, early 2000s)
ধরনExperimental design — adaptive variant of RCTExperimental design
মৌলিক উৎসChow, S.-C., & Chang, M. (2008). Adaptive Design Methods in Clinical Trials. Chapman & Hall/CRC. ISBN: 978-1584887690Royston, P., Parmar, M. K. B., & Qian, W. (2003). Novel designs for multi-arm clinical trials with survival outcomes with an application in ovarian cancer. Statistics in Medicine, 22(14), 2239–2256. DOI ↗
অপর নামAdaptive RCT, Response-adaptive RCT, Adaptive clinical trial, Platform trialmulti-arm trial, multiple-arm experiment, multi-group experiment, many-arm design
সম্পর্কিত65
সারসংক্ষেপAn adaptive randomized controlled trial (adaptive RCT) is an experimental design in which pre-specified rules allow modifications to the trial while it is ongoing — such as changing allocation ratios, dropping underperforming arms, or stopping early for efficacy or futility — based on accumulating interim data. These adaptations are planned before the trial starts and governed by statistical rules to preserve Type I error control and validity.A multi-arm experiment simultaneously compares three or more treatment or intervention conditions — each called an arm — against a shared control or against one another. By testing multiple alternatives in a single study, it yields more information per participant than running separate two-group experiments sequentially, while controlling the overall Type I error rate through pre-specified comparison strategies.
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ScholarGateপদ্ধতির তুলনা করুন: Adaptive Randomized Controlled Trial · Multi-arm experiment. 2026-06-17 তারিখে সংগৃহীত, উৎস: https://scholargate.app/bn/compare