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Проспективен анализ на зависимостта доза-отговор×Анализ „доза-отговор“×
ОбластЕпидемиологияЕпидемиология
СемействоProcess / pipelineProcess / pipeline
Година на възникване1965 (Hill's criteria); widely applied through 1980s–presentConceptual roots 16th century; modern epidemiological application mid-20th century
СъздателBradford Hill (causal criteria including dose-response, 1965); formalized in modern epidemiology by Rothman, Greenland and othersParacelsus (conceptual foundation); formalized by John Snow and later Bradford Hill
ТипAnalytical epidemiological study designQuantitative analytical method
Основополагащ източникRothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755641Rothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755641
Други названияprospective exposure-response analysis, prospective trend analysis, forward-looking dose-response study, prospective gradient analysisexposure-response analysis, concentration-response modeling, dose-response modeling, DRA
Свързани44
РезюмеProspective dose-response analysis is an epidemiological approach that measures exposure levels in a defined population before outcomes occur, then quantifies how the risk or magnitude of an outcome changes systematically as exposure increases. By collecting exposure data prospectively, researchers can establish temporal sequence, reduce recall bias, and assess whether a biological gradient — one of Hill's classic causal criteria — exists between the agent of interest and a health outcome.Dose-response analysis quantifies the relationship between the magnitude of an exposure (the dose) and the probability or rate of an outcome (the response). It is a core analytical strategy in epidemiology and toxicology, providing evidence that increasing exposure systematically increases — or decreases — the risk of disease. A demonstrated dose-response gradient is one of Bradford Hill's classic criteria supporting causal inference.
ScholarGateНабор от данни
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  2. 2 Източници
  3. PUBLISHED
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ScholarGateСравнение на методи: Prospective Dose-Response Analysis · Dose-Response Analysis. Извлечено на 2026-06-18 от https://scholargate.app/bg/compare