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كروماتوغرافيا العمود×تخطيط مسار التخليق×
المجالالكيمياءالكيمياء
العائلةProcess / pipelineProcess / pipeline
سنة النشأة19031969
صاحب الطريقةMikhail TsvetElias James Corey
النوعChromatographic separation techniqueStrategic planning methodology
المصدر التأسيسيSkoog, D. A., Holler, F. J., & Crouch, S. R. (2017). Principles of Instrumental Analysis (7th ed.). Cengage Learning. ISBN: 978-1305577213Corey, E. J., & Cheng, X. M. (1991). The Logic of Chemical Synthesis. John Wiley & Sons. ISBN: 978-0471096092
الأسماء البديلةliquid chromatography, column liquid chromatographyretrosynthesis, retrosynthetic analysis, synthetic route design
ذات صلة33
الملخصColumn chromatography is a liquid separation technique in which a stationary phase (typically silica gel or alumina) is packed into a vertical column, and a mobile phase (solvent) percolates through it to separate mixture components. Pioneered by Mikhail Tsvet in 1903, column chromatography remains the workhorse of organic chemistry laboratories for purifying reaction products and isolating target compounds.Synthesis route planning, grounded in retrosynthetic analysis, is a strategic approach to designing efficient chemical syntheses. Formalized by Elias James Corey in the 1960s (earning him the Nobel Prize in 1990), this methodology systematically deconstructs target molecules into simpler precursors and starting materials, enabling chemists to discover logical, economical, and practical synthesis routes.
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ScholarGateقارن الطرق: Column Chromatography · Synthesis Route Planning. استُرجع بتاريخ 2026-06-18 من https://scholargate.app/ar/compare