Crossover Fractional Factorial Experiment
A crossover fractional factorial experiment is a within-subject design in which each participant receives a strategically chosen subset of all possible factor-level combinations in a defined sequence, with washout periods between treatment periods. By combining the run-economy of fractional factorial designs with the within-subject efficiency of crossover designs, it allows estimation of main effects and selected interactions while controlling for between-subject variability using far fewer participants and experimental runs than a full factorial crossover.
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- Senn, S. (2002). Cross-over Trials in Clinical Research (2nd ed.). Wiley. · ISBN 978-0471496533
- Box, G. E. P., Hunter, J. S., & Hunter, W. G. (2005). Statistics for Experimenters: Design, Innovation, and Discovery (2nd ed.). Wiley. · ISBN 978-0471718130
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