Case Report
A case report is a detailed clinical account of one patient's diagnosis, treatment, and outcome, typically used to describe novel, unusual, or educational cases not previously reported. Unlike controlled studies with comparison groups, case reports are observational, non-comparative, and generate hypotheses rather than test them. Occupying the lowest rung of evidence hierarchy, case reports are nonetheless valuable for early signal detection, documenting rare diseases, and communicating clinical wisdom. The CARE guidelines (2013) provide reporting standards to ensure completeness and transparency.
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- Gagnier, J. J., Kienle, G., Altman, D. G., Moher, D., Lakatos, P., & Conboy, T. A. (2013). The CARE guidelines: consensus-based clinical case report guideline development. Journal of Clinical Epidemiology, 67(1), 46–51. · DOI 10.1016/j.jclinepi.2013.08.003
- CARE Guidelines Checklist (2013). Enhancing the Quality and Transparency of Health Research. http://www.care-statement.org · URL
- Nissen, S. E., & Wolski, K. (2007). Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. New England Journal of Medicine, 356(24), 2457–2471. · DOI 10.1056/NEJMoa072761
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