Magnetic Resonance Elastography
Magnetic Resonance Elastography (MRE) is a non-invasive imaging technique that measures tissue stiffness by encoding the motion of acoustic shear waves into MRI signal and calculating the elastic modulus from wave propagation patterns. Developed by Muthupillai and colleagues in 1995, MRE enables quantitative assessment of tissue mechanics, particularly useful for diagnosing liver fibrosis, cardiac dysfunction, and neurological diseases. It has emerged as a non-invasive alternative to biopsy for staging hepatic fibrosis and is expanding into other organ systems.
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- Muthupillai, R., Lomas, D. J., Rossman, P. J., et al. (1995). Magnetic resonance elastography by direct visualization of propagating acoustic strain waves. Science, 269(5232), 1854-1857. · DOI 10.1126/science.7569924
- Huwart, L., Sempoux, C., Vicaut, E., et al. (2008). Magnetic resonance elastography for the noninvasive staging of liver fibrosis. Gastroenterology, 135(1), 32-40. · DOI 10.1053/j.gastro.2008.03.076
- Kolipaka, A., McGee, K. P., Araoz, P. A., et al. (2008). Magnetic resonance elastography as a method for the assessment of myocardial stiffness: Concepts and applications. Journal of Cardiovascular Magnetic Resonance, 10(1), 43. · URL
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