Central Sensitization Inventory
The Central Sensitization Inventory (CSI) is a 25-item self-report screening instrument developed by Mayer and colleagues in 2012 to identify patients with central sensitization—a condition characterized by amplification of pain signaling and hypersensitivity to sensory stimuli. The CSI captures the constellation of symptoms including widespread pain, sleep disturbance, cognitive dysfunction, and autonomic dysregulation associated with central sensitization syndromes such as fibromyalgia, chronic fatigue syndrome, and post-traumatic stress disorder.
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- Mayer, T.G., Neblett, R., Cohen, H., et al. (2012). The development and psychometric validation of the Central Sensitization Inventory. Pain Practice, 12(4), 276-285. · DOI 10.1111/j.1533-2500.2011.00493.x
- Neblett, R., Cohen, H., Choi, Y., Hardin, J.W., Mayer, T.G., Gonder-Frederick, L.A., & Mayer, J.M. (2013). The Central Sensitization Inventory (CSI): Establishing clinically significant values for identifying central sensitization in an outpatient chronic pain population. Journal of Pain, 14(5), 438-445. · DOI 10.1016/j.jpain.2012.11.012
- Schilling, J.M., Koh, S.E., Tully, A.S., et al. (2018). Central sensitization phenotyping in patients with knee osteoarthritis. Clinical Journal of Pain, 34(4), 296-302. · URL
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