Deficit-Accumulation Frailty Index
The deficit-accumulation frailty index measures frailty as the proportion of a long list of age-related health deficits that a person has accumulated. Introduced by Arnold Mitnitski and Kenneth Rockwood in 2001, it treats frailty not as a fixed syndrome but as a quantitative state: the more things have gone wrong across many body systems, the frailer the person. Counting 30 or more deficits — symptoms, signs, diseases, disabilities, and laboratory abnormalities — and dividing by the number considered yields a continuous score between 0 and 1 that rises with age, predicts mortality and adverse outcomes, and behaves remarkably consistently regardless of exactly which deficits are used. A standardized procedure by Searle and colleagues made the index easy to construct from existing data.
Bronrecord
Citaten letterlijk overgenomen uit het bronrecord van de methode. Hieruit wordt geen verificatie op claimniveau afgeleid.
- Mitnitski, A. B., Mogilner, A. J., & Rockwood, K. (2001). Accumulation of deficits as a proxy measure of aging. The Scientific World Journal, 1, 323-336. · DOI 10.1100/tsw.2001.58
- Searle, S. D., Mitnitski, A., Gahbauer, E. A., Gill, T. M., & Rockwood, K. (2008). A standard procedure for creating a frailty index. BMC Geriatrics, 8, 24. · DOI 10.1186/1471-2318-8-24
Gecureerde claims
Claims opgeslagen in het bewijsregister, elk met zijn eigen beoordeling.
Deze weergave verzint geen claimbeoordeling als het register er geen heeft.
Gerelateerde methoden
Gegenereerd uit de methodegraaf en getoond als machinaal voorgestelde relaties — er wordt geen bewijsclaim afgeleid.