Σύγκριση μεθόδων
Εξετάστε τις επιλεγμένες μεθόδους δίπλα-δίπλα· οι γραμμές που διαφέρουν επισημαίνονται.
| Πραγματιστικός Σχεδιασμός Πειραματικής Ομάδας Ελέγχου× | Πειραματικός Σχεδιασμός Crossover με Ομάδα Ελέγχου× | |
|---|---|---|
| Πεδίο | Πειραματικός Σχεδιασμός | Πειραματικός Σχεδιασμός |
| Οικογένεια | Process / pipeline | Process / pipeline |
| Έτος προέλευσης≠ | 1967 (seminal distinction); 2009 (PRECIS operationalization) | Mid-20th century; systematic treatment from 1980s onward |
| Δημιουργός≠ | Schwartz & Lellouch (pragmatic vs explanatory distinction); extended by PRECIS framework (Thorpe et al.) | Established in clinical pharmacology and agricultural research; formalized by B. Jones & M. G. Kenward |
| Τύπος≠ | Experimental design (pragmatic variant) | Experimental design |
| Θεμελιώδης πηγή≠ | Schwartz, D., & Lellouch, J. (1967). Explanatory and pragmatic attitudes in therapeutical trials. Journal of Chronic Diseases, 20(8), 637–648. DOI ↗ | Jones, B., & Kenward, M. G. (2003). Design and Analysis of Cross-Over Trials (2nd ed.). Chapman and Hall/CRC. ISBN: 978-1584883500 |
| Εναλλακτικές ονομασίες | pragmatic controlled trial, effectiveness trial with control group, real-world control group design, pragmatic comparative design | crossover controlled trial, within-subject crossover with control, AB/BA crossover controlled design, repeated-measures crossover with control arm |
| Συναφείς | 6 | 6 |
| Σύνοψη≠ | A pragmatic control group experimental design tests whether an intervention works under routine, real-world conditions by comparing it against a control condition — typically usual care or an active comparator — rather than a tightly controlled placebo. It prioritises external validity and applicability over the internal purity of an explanatory efficacy trial, asking whether an intervention makes a meaningful difference to people as they are actually treated in practice. | A crossover control group experimental design is an experimental approach in which participants are randomly assigned to sequences of conditions that include both a treatment and a control (no-treatment or placebo) period, with each participant experiencing both the experimental and control conditions in succession. By using each participant as their own control across periods, this design sharply reduces between-subject variability and typically requires fewer participants than parallel group trials to achieve equivalent statistical power. |
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