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| Εκτιμητής Αθροιστικού Κινδύνου Nelson-Aalen× | Παλινδρόμηση Αναλογικών Κινδύνων του Cox× | Μοντέλο Κοινής Αδυναμίας για Ομαδοποιημένα Δεδομένα Επιβίωσης× | |
|---|---|---|---|
| Πεδίο | Ανάλυση Επιβίωσης | Ανάλυση Επιβίωσης | Ανάλυση Επιβίωσης |
| Οικογένεια | Survival analysis | Survival analysis | Survival analysis |
| Έτος προέλευσης≠ | 1972 | 1972 | 1979 |
| Δημιουργός≠ | Wayne Nelson & Odd Aalen | Cox, D. R. | Vaupel, J.W., Manton, K.G. & Stallard, E. |
| Τύπος≠ | Non-parametric cumulative hazard estimator | Semi-parametric hazard regression model | Random effects survival model |
| Θεμελιώδης πηγή≠ | Nelson, W. (1972). Theory and applications of hazard plotting for censored failure data. Technometrics, 14(4), 945–966. DOI ↗ | Cox, D. R. (1972). Regression Models and Life-Tables. Journal of the Royal Statistical Society: Series B, 34(2), 187–202. DOI ↗ | Vaupel, J.W., Manton, K.G. & Stallard, E. (1979). The Impact of Heterogeneity in Individual Frailty on the Dynamics of Mortality. Demography, 16(3), 439–454. DOI ↗ |
| Εναλλακτικές ονομασίες≠ | Nelson-Aalen cumulative hazard, Aalen estimator, empirical cumulative hazard, Nelson-Aalen kümülatif hazard tahmincisi | cox ph model, proportional hazards model, cox ph regression, Cox Orantılı Tehlikeler Regresyonu | shared frailty model, random effects survival model, Frailty Modeli (Paylaşılan Kırılganlık) |
| Συναφείς≠ | 5 | 3 | 3 |
| Σύνοψη≠ | The Nelson-Aalen estimator is a non-parametric estimator of the cumulative hazard function from right-censored time-to-event data. Developed by Wayne Nelson for reliability hazard plotting in 1972 and placed on a rigorous counting-process foundation by Odd Aalen in 1978, it accumulates the ratio of observed events to the number at risk at each event time, providing the natural hazard-scale companion to the Kaplan-Meier survival curve. | Cox proportional hazards regression, introduced by D. R. Cox in 1972, is a semi-parametric model that estimates how one or more covariates affect the hazard — the instantaneous rate of experiencing an event — while leaving the baseline hazard function unspecified. It is the standard multivariable method in survival analysis and produces hazard ratios that quantify the relative risk associated with each predictor. | The shared frailty model, introduced by Vaupel, Manton, and Stallard in 1979, extends standard survival regression by incorporating a random effect — the 'frailty' — that captures unobserved heterogeneity among subjects or clusters. When survival outcomes are measured on individuals who share a common environment (patients in the same hospital, members of the same family, animals in the same litter), a frailty term accounts for the within-cluster dependence that ordinary Cox regression ignores. |
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