Meta-analytic dose-response analysis
Meta-analytic dose-response analysis pools summary statistics from multiple epidemiological studies to characterize how disease risk changes across ordered levels of an exposure. Rather than comparing a single high-exposure group against a reference, it reconstructs a continuous or categorical exposure-risk curve across the full range of doses, providing far richer evidence about the shape and magnitude of an association than any single study can supply.
Kilderegistrering
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- Greenland, S., & Longnecker, M. P. (1992). Methods for trend estimation from summarized dose-response data, with applications to meta-analysis. American Journal of Epidemiology, 135(11), 1301–1309. · DOI 10.1093/oxfordjournals.aje.a116237
- Orsini, N., Li, R., Wolk, A., Khudyakov, P., & Spiegelman, D. (2012). Meta-analysis for linear and nonlinear dose-response relations: Examples, an evaluation of approximations, and software. American Journal of Epidemiology, 175(1), 66–73. · DOI 10.1093/aje/kwr265
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